Synthesis, characterisation and luminescence properties of MCM-41 impregnated with an Eu3+ β-diketonate complex Abstract A luminescent material has been prepared by formation of the Eu3+ β-diketonate complex Eu(NTA)3L″ {NTA = 1-(2-naphthoyl)-3,3,3-trifluoroacetonate; L″ = ethyl[3-(2-pyridyl)-1-pyrazolyl]acetate} within the channels of MCM-41-type ordered mesoporous silica. Using simple wet impregnation methods, the ligand L″ was first encapsulated followed by…

Pseudopolymorphic transitions of niclosamide monitored by Raman spectroscopy. Abstract “Niclosamide suffers pseudopolymorphic transformations when exposed to different ambient conditions, which can lead to changes in its bioavailability. In this study, the kinetics of the pseudopolymorphic transitions of niclosamide crystals are characterized. FT-Raman spectroscopy is used to quantify the anhydrate and hydrate forms of niclosamide crystals,…

A Combined Theoretical-Experimental Study of the Inclusion of Niobocene Dichloride in Native and Permethylated ß-Cyclodextrins Abstract Inclusion complexes comprising niobocene dichloride, Cp2NbCl2, and either native β-cyclodextrin (β-CD) or permethylated β-CD (TRIMEB) were prepared with a host:guest molar ratio of 1:1. The adducts were characterized in the solid state by powder X-ray diffraction (XRD), thermogravimetric analysis…

Synthesis and catalytic properties in olefin epoxidation of dioxomolybdenum(VI) complexes bearing a bidentate or tetradentate salen-type ligand Abstract The monomeric cis-dioxomolybdenum(VI) complexes [MoO2(oep-saldpen)] and [MoO2Cl2(oep-H2saldpen)], with a tetradentate [N2(imine)O2] and bidentate [N2(imine)] salen-type ligand functionalised with two pyrrole derivative pendant arms [oep-H2saldpen = 1,2-diphenylethylenebis(3-oxyethylpyrrole)salicylideneimine], were synthesised and characterised by 1H NMR, IR and Raman spectroscopy….

Probing Pseudo-Polymorphic Transitions in Pharmaceutical Solids using Raman Spectroscopy: Hydration and Dehydration of Theophylline. Abstract Theophylline is known to undergo vapor phase induced hydrate–anhydrate pseudopolymorphic transformations, which can affect its bioavailability. In this work, the kinetics of the pseudopolymorphic transitions of theophylline crystals in different storage conditions is studied using a vibrational spectroscopic technique. While…